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001 978-1-4939-3743-1
003 DE-He213
005 20190313085124.0
007 cr nn 008mamaa
008 161103s2017 xxu| s |||| 0|eng d
020 _a9781493937431
_9978-1-4939-3743-1
024 7 _a10.1007/978-1-4939-3743-1
_2doi
050 4 _aQH324.2-324.25
072 7 _aPSD
_2bicssc
072 7 _aUB
_2bicssc
072 7 _aSCI056000
_2bisacsh
082 0 4 _a570.285
_223
245 1 4 _aThe Gene Ontology Handbook
_h[electronic resource] /
_cedited by Christophe Dessimoz, Nives Škunca.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Humana Press,
_c2017.
300 _aXII, 305 p. 56 illus., 50 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1064-3745 ;
_v1446
505 0 _aPrimer on Ontologies -- The Gene Ontology and the Meaning of Biological Function -- Primer on the Gene Ontology -- Best Practices in Manual Annotation with the Gene Ontology -- Computational Methods for Annotation Transfers from Sequence -- Text Mining to Support Gene Ontology Curation and Vice Versa -- How Does the Scientific Community Contribute to Gene Ontology? -- Evaluating Computational Gene Ontology Annotations -- Evaluating Functional Annotations of Enzymes Using the Gene Ontology -- Community-Based Evaluation of Computational Function Prediction -- Get GO!: Retrieving GO Data Using AmiGO, QuickGO, API, Files, and Tools -- Semantic Similarity in the Gene Ontology -- Gene-Category Analysis -- Gene Ontology: Pitfalls, Biases, and Remedies -- Visualizing GO Annotations -- A Gene Ontology Tutorial in Python -- Annotation Extensions -- The Evidence and Conclusion Ontology (ECO): Supporting GO Annotations -- Complementary Sources of Protein Functional Information: The Far Side of GO -- Integrating Bio-Ontologies and Controlled Clinical Terminologies: From Base Pairs to Bedside Phenotypes -- The Vision and Challenges of the Gene Ontology.
506 0 _aOpen Access
520 _aThis book is open access under a CC BY 4.0 license. This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system.
650 0 _aLife sciences.
650 0 _aBioinformatics.
650 1 4 _aLife Sciences.
650 2 4 _aBioinformatics.
700 1 _aDessimoz, Christophe.
_eeditor.
700 1 _aŠkunca, Nives.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781493937417
830 0 _aMethods in Molecular Biology,
_x1064-3745 ;
_v1446
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4939-3743-1
856 4 0 _uhttp://www.springerprotocols.com/doiresolver?genre=book&pid=10.1007/978-1-4939-3743-1
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999 _c48280
_d48280